Take a big problem, apply the best minds to its prospects, add the fuel of entrepreneurial energy and a touch of capitalist greed, and one has the perfect recipe for solving any social, environmental, or cultural dilemma, says Khosla Ventures' Vinod Khosla. Mere good intentions are not enough to invoke real change. But the course of industry can only be altered when all angles of the problem-solving pyramid are in place. 

Tina Seelig, Executive Director of the Stanford Technology Ventures Program, walks us through a life-changing hands-on classroom activity where students are taught to identify opportunities in nooks and crannies. With five dollars in seed funding and two hours of execution, she reports on the success of the exercise, and that many students reaped over one hundred times the initial investment (and others built a business without using any funding at all). Look for problems around you, says Seelig, and convert them into opportunities that create value. Embrace the opportunity to challenge assumptions and identify true cultural, social, or technological need. 

Komisar talks about what he looks forward to in his career and life. He advises others who are unsure about the future to find ways to optimize their situation, the people they work with, and the flow of available opportunities. He also notes that the notion of being in motion is an important aspect of who he is and what he enjoys doing.  

Tom Kelley, general manager at the world-renowned design firm, IDEO, presents five core practices that enhance creativity. Through entertaining stories and examples, he describes how these techniques help us all become more innovative in every aspect of our lives and lead to more success. 

As a research scientist at Stanford University, Anna Patterson committed herself to indexing the world's online information. Her latest venture, Cuil (pronounced "cool") is a search engine that is challenging Google. She explains how she is using her experience with startups and non-profits to take on her former employer.