When the economy looks down, entrepreneurs look up. Check out our series on innovating during a crisis.

How to Operate in a Downturn Economy

Gordon Ringold, Affymax Research Institute

Surromed has had to adapt its business plan, downsize the company, and pair down numbers of diseases, says Ringold. Things are very different from when they started the company. To be stronger when markets open up and to start a company today, one must build slowly and be flexible, he notes.